Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(1-Methylcyclohexyl)acetic acid → 1-[6-Chloro-5-[[(1-methylcyclohexyl)acetyl]amino]-2-quinolinyl]-4-piperidinecarboxylic acid, ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(1-Methylcyclohexyl)acetic acid | HCID 13697885 | — |
| 반응물 | Ethyl 1-(5-amino-6-chloroquinolin-2-yl)piperidine-4-carboxylate | HCID 69320002 | — |
| 생성물 | 1-[6-Chloro-5-[[(1-methylcyclohexyl)acetyl]amino]-2-quinolinyl]-4-piperidinecarboxylic acid, ethyl ester | HCID 86609746 | 70.7% |
반응 단계
Prepared according to the method of example 62(a), using 1-methyl-cyclohexaneacetic acid (280 mg) and 1-(5-amino-6-chloro-2-quinolinyl)-4-piperidinecarboxylic acid, ethyl ester (Example 77(a)) (200 mg), to afford the sub-titled compound (200 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07408065B2 |
| 출처 데이터셋 | uspto-grants-2008_08 |
| ORD ID | ord-efecbd211baa4771ad7fd3b6864c7b93 |
| 출처 메모 | uspto-grants-2008_08 |