Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Piperidinecarbonitrile hydrochloride → 6-Chloro-2-(4-cyano-1-piperidinyl)-N-(2-cyclohexylethyl)-5-quinolinecarboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Piperidinecarbonitrile hydrochloride | HCID 22744637 | — |
| 반응물 | 2,6-Dichloro-N-(2-cyclohexylethyl)-5-quinolinecarboxamide | HCID 86012861 | — |
| 생성물 | 6-Chloro-2-(4-cyano-1-piperidinyl)-N-(2-cyclohexylethyl)-5-quinolinecarboxamide | HCID 68809649 | 28.3% |
반응 단계
Prepared according to the method of example 51, using 2,6-dichloro-N-(cyclohexylethyl)-5-quinolinecarboxamide (Example 94 (d)) (0.35 g), and 4-cyanopiperidine hydrochloride (0.25 g) to afford the title compound (0.12 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07408065B2 |
| 출처 데이터셋 | uspto-grants-2008_08 |
| ORD ID | ord-80495ad9d07746538a204bcee4b5025c |
| 출처 메모 | uspto-grants-2008_08 |