3-Thiophenemethylamine → 3-Nitro-4-[(3-thienylmethyl)amino]-N,N-bis(2,2,2-trifluoroethyl)benzamide

HRID 2217940

반응식

HRID 2217940 반응식
F[C:2]1[CH:20]=[CH:19][C:5]([C:6]([N:8]([CH2:14][C:15]([F:18])([F:17])[F:16])[CH2:9][C:10]([F:13])([F:12])[F:11])=[O:7])=[CH:4][C:3]=1[N+:21]([O-:23])=[O:22].[S:24]1[CH:28]=[CH:27][C:26]([CH2:29][NH2:30])=[CH:25]1>CCO>[N+:21]([C:3]1[CH:4]=[C:5]([CH:19]=[CH:20][C:2]=1[NH:30][CH2:29][C:26]1[CH:27]=[CH:28][S:24][CH:25]=1)[C:6]([N:8]([CH2:9][C:10]([F:12])([F:13])[F:11])[CH2:14][C:15]([F:17])([F:18])[F:16])=[O:7])([O-:23])=[O:22]

참가 물질

4

반응물 2

HCID 27763813-ThiophenemethylamineHCID 589117444-Fluoro-3-nitro-N,N-bis(2,2,2-trifluoroethyl)benzamide

생성물 1

HCID 588744973-Nitro-4-[(3-thienylmethyl)amino]-N,N-bis(2,2,2-trifluoroethyl)benzamide

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

Following the general procedure for Intermediate 2 using 4-fluoro-3-nitro-N,N-bis(2,2,2-trifluoroethyl)benzamide (125 mg, 0.359 mmol) and 3-thienylmethylamine (49 mg, 0.431 mmol) in 3 mL of EtOH containing TEA (0.075 mL, 0.539 mmol).

출처 및 근거

ORD 기록
ord-aae50351a47f408185bf7e833ea1afb0
출처 데이터셋
uspto-grants-2008_08
특허 번호
US07407968B2

연결된 노트

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