5-Chlorothiophene-2-sulfonyl chloride → 5-Chloro-N-(3-bromo-6-chloro-2-pyrazinyl)-2-thiophenesulphonamide

반응식

[Br:1][C:2]1[C:3]([NH2:9])=[N:4][C:5]([Cl:8])=[CH:6][N:7]=1.[Cl:10][C:11]1[S:15][C:14]([S:16](Cl)(=[O:18])=[O:17])=[CH:13][CH:12]=1>>[Cl:10][C:11]1[S:15][C:14]([S:16]([NH:9][C:3]2[C:2]([Br:1])=[N:7][CH:6]=[C:5]([Cl:8])[N:4]=2)(=[O:18])=[O:17])=[CH:13][CH:12]=1

참가 물질

반응물 2

HCID 27339255-Chlorothiophene-2-sulfonyl chloride

HCID 179559912-Amino-3-bromo-6-chloropyrazine

생성물 1

HCID 102159965-Chloro-N-(3-bromo-6-chloro-2-pyrazinyl)-2-thiophenesulphonamide

실험 절차

Prepared by the method of Example 1 using 3-bromo-6-chloro-2-pyrazinamine and 5-chloro-2-thienylsulphonyl chloride.

출처 및 근거

ORD 기록: ord-0b772aeb2cac4849bb2879f8193d364b
출처 데이터셋: uspto-grants-2008_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07410972B2

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