2-Amino-5-chloro-3-methoxypyrazine → N-[5-Chloro-3-methoxy-2-pyrazinyl]-5-methyl-2-thiophenesulphonamide

반응식

[CH3:1][C:2]1[S:6][C:5]([S:7](Cl)(=[O:9])=[O:8])=[CH:4][CH:3]=1.[Cl:11][C:12]1[N:13]=[C:14]([O:19][CH3:20])[C:15]([NH2:18])=[N:16][CH:17]=1>>[Cl:11][C:12]1[N:13]=[C:14]([O:19][CH3:20])[C:15]([NH:18][S:7]([C:5]2[S:6][C:2]([CH3:1])=[CH:3][CH:4]=2)(=[O:9])=[O:8])=[N:16][CH:17]=1

참가 물질

반응물 2

HCID 107970362-Amino-5-chloro-3-methoxypyrazine

HCID 124001125-Methylthiophene-2-sulfonyl chloride

생성물 1

HCID 10149749N-[5-Chloro-3-methoxy-2-pyrazinyl]-5-methyl-2-thiophenesulphonamide

실험 절차

Prepared by the method of Example 1 using 5-methylthiophenesulphonyl chloride and 5-chloro-3-methoxy-2-pyrazinamine.

출처 및 근거

ORD 기록: ord-b2c5da34f1fa4a33b4579fe475d0eb54
출처 데이터셋: uspto-grants-2008_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07410972B2

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