3-(4-Hydroxymethylphenyl)acrylic acid ethyl ester → Ethyl 3-(4-(hydroxymethyl)phenyl)propanoate

HRID 2218118노트

반응식

HRID 2218118 반응식
[CH2:1]([O:3][C:4](=[O:15])[CH:5]=[CH:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][OH:14])=[CH:9][CH:8]=1)[CH3:2].[H][H]>[Pd].C(O)C>[CH2:1]([O:3][C:4](=[O:15])[CH2:5][CH2:6][C:7]1[CH:8]=[CH:9][C:10]([CH2:13][OH:14])=[CH:11][CH:12]=1)[CH3:2]

참가 물질

5

반응물 2

HCID 684575823-(4-Hydroxymethylphenyl)acrylic acid ethyl esterHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 14839455Ethyl 3-(4-(hydroxymethyl)phenyl)propanoate

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

3-(4-Hydroxymethylphenyl)acrylic acid ethyl ester (P4, 3 g, 14.5 mmol) and palladium on charcoal (0.3 g) in ethanol (30 mL) was stirred for 4 hours under atmospheric pressure of hydrogen. The reaction mixture was filtered through celite (Diatomaceous Earth) and concentrated to afford the title compound as an oil.

후처리

  1. filtrationThe reaction mixture was filtered through celite (Diatomaceous Earth)
  2. concentrationconcentrated

출처 및 근거

ORD 기록
ord-88962a19cc68445dac2f54de163f87b2
출처 데이터셋
uspto-grants-2008_08
특허 번호
US07410984B2

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