Trifluoroacetic acid → HCID 178484433, 화합물

반응식

[Br:1][C:2]1[CH:3]=[C:4]2[N:10]=[C:9]([C:11]3[CH:16]=[CH:15][C:14]([OH:17])=[CH:13][CH:12]=3)[NH:8][C:5]2=[N:6][CH:7]=1.Br[CH2:19][CH2:20][N:21](C)[C:22](=O)OC(C)(C)C.FC(F)(F)C(O)=O>>[Br:1][C:2]1[CH:3]=[C:4]2[N:10]=[C:9]([C:11]3[CH:12]=[CH:13][C:14]([O:17][CH2:19][CH2:20][NH:21][CH3:22])=[CH:15][CH:16]=3)[NH:8][C:5]2=[N:6][CH:7]=1

참가 물질

반응물 3

HCID 6422Trifluoroacetic acid

HCID 53743212HCID 53743212, 화합물

HCID 178515890HCID 178515890, 화합물

생성물 1

HCID 178484433HCID 178484433, 화합물

실험 절차

The title compound was prepared from 4-(6-bromo-3H-imidazo[4,5-b]pyridin-2-yl)phenol and tert-butyl 2-bromoethyl(methyl)carbamate using the method described in Example 41, followed by deprotection using trifluoroacetic acid.

출처 및 근거

ORD 기록: ord-1b416a1ebfbf40a8933c48cffe35cef2
출처 데이터셋: uspto-grants-2008_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07410966B2

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