Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(4-Methanesulfonamidophenyl)boronic acid → N-[4-(1-Chloro-10,11-dihydro-dibenzo[a,d]cyclohepten-5ylidenemethyl)-phenyl]-methanesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (4-Methanesulfonamidophenyl)boronic acid | HCID 2773537 | — |
| 반응물 | 5-bromomethylene-1-chloro-10,11dihydro-5H-dibenzo[a,d]cycloheptene | HCID 68891389 | — |
| 생성물 | N-[4-(1-Chloro-10,11-dihydro-dibenzo[a,d]cyclohepten-5ylidenemethyl)-phenyl]-methanesulfonamide | HCID 68939940 | — |
반응 단계
Following procedures essentially as described in Example 219, below, and using 5-bromomethylene-1-chloro-10,11-dihydro-5H-dibenzo[a,d]cycloheptene (100 mg, 0.313 mmol) and 4-methanesulfonylaminophenylboronic acid (74 mg, 0.344 mmol), affords 55 mg (43%) of a mixture of geometric isomers of the title compound as a brown oil. MS (ES) 408 (M−H); HPLC shows 96% purity.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07411072B2 |
| 출처 데이터셋 | uspto-grants-2008_08 |
| ORD ID | ord-a25755dac67a440dabdde3de210b8e93 |
| 출처 메모 | uspto-grants-2008_08 |