3-Bromo-4-methylpyridine → HCID 25097153, 화합물

반응식

[F:1][C:2]([F:26])([F:25])[C:3]1[N:4]=[C:5]([NH:8][C:9]([C:11]2[C:16]([NH:17][C:18]3[CH:19]=[N:20][CH:21]=[CH:22][CH:23]=3)=[CH:15][CH:14]=[C:13]([CH3:24])[N:12]=2)=[O:10])[S:6][CH:7]=1.Br[C:28]1C=NC=CC=1C>>[F:26][C:2]([F:1])([F:25])[C:3]1[N:4]=[C:5]([NH:8][C:9]([C:11]2[C:16]([NH:17][C:18]3[CH:19]=[N:20][CH:21]=[CH:22][C:23]=3[CH3:28])=[CH:15][CH:14]=[C:13]([CH3:24])[N:12]=2)=[O:10])[S:6][CH:7]=1

참가 물질

반응물 2

HCID 8176303-Bromo-4-methylpyridine

HCID 11588965HCID 11588965, 화합물

생성물 1

HCID 25097153HCID 25097153, 화합물

실험 절차

The title compound, was prepared from 3-Amino-6-methyl-pyridine-2-carboxylic acid (4-trifluoromethyl-thiazol-2-yl)-amide (example 18) and 3-Bromo-4-methylpyridine in accordance with the general method of example 20 to yield the final compound as a orange solid, MS (ISP): m/e=394.0 (M+H+).

출처 및 근거

ORD 기록: ord-cd91767083724d7ebe3f8d1fabf6724d
출처 데이터셋: uspto-grants-2008_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07414060B2

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