2-Methyl-1,3-thiazol-4-amine → 6-Methyl-3-(5-methyl-pyridin-3-ylamino)-pyridine-2-carboxylic acid (2-methyl-thiazol-4-yl)-amide

HRID 2219568

반응식

HRID 2219568 반응식
C(O[C:4]([C:6]1[C:11]([NH:12][C:13]2[CH:14]=[N:15][CH:16]=[C:17]([CH3:19])[CH:18]=2)=[CH:10][CH:9]=[C:8]([CH3:20])[N:7]=1)=[O:5])C.[NH2:21][C:22]1[N:23]=[C:24]([CH3:27])[S:25][CH:26]=1>>[CH3:27][C:24]1[S:25][CH:26]=[C:22]([NH:21][C:4]([C:6]2[C:11]([NH:12][C:13]3[CH:14]=[N:15][CH:16]=[C:17]([CH3:19])[CH:18]=3)=[CH:10][CH:9]=[C:8]([CH3:20])[N:7]=2)=[O:5])[N:23]=1

참가 물질

3

실험 절차

The title compound, was prepared from 6-Methyl-3-(5-methyl-pyridin-3-ylamino)-pyridine-2-carboxylic acid ethyl ester and 4-Amino-2-methylthiazole in accordance with the general method of Example 78, step 2 to yield the final compound as a light-yellow solid, MS (ISP): m/e=340.1 (M+H+).

출처 및 근거

ORD 기록
ord-3364b361cba149b7940241c028849c5f
출처 데이터셋
uspto-grants-2008_08
특허 번호
US07414060B2

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