Pyrimidin-5-amine → HCID 58368048, 화합물
반응식
[CH2:1]([O:3][C:4]([C:6]1[C:11](Br)=[CH:10][CH:9]=[C:8]([CH:13]2[CH2:15]C2)[N:7]=1)=[O:5])[CH3:2].[NH2:16][C:17]1[CH:18]=[N:19][CH:20]=[N:21][CH:22]=1>[Pd]>[CH2:1]([O:3][C:4]([C:6]1[C:11]([NH:16][C:17]2[CH:18]=[N:19][CH:20]=[N:21][CH:22]=2)=[CH:10][CH:9]=[C:8]([CH2:13][CH3:15])[N:7]=1)=[O:5])[CH3:2]참가 물질
4
실험 절차
Palladium catalysed arylation of 3-Bromo-6-cyclopropyl-pyridine-2-carboxylic acid ethyl ester with 5-Aminopyrimidine according to the general procedure described in example 78 step 3 yielded the title compound as a white solid, MS (ISP): m/e=273.3 (M+H+).
출처 및 근거
- ORD 기록
- ord-b2ebd6fda760442dbc92bfbe949d0715
- 출처 데이터셋
- uspto-grants-2008_08
- 특허 번호
- US07414060B2
반응 노트
불러오는 중…