Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-cyclohexyl-N-thiazol-2-yl-1-(4-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetamide → N-cyclohexyl-N-thiazol-2-yl-5-methoxy-2-methylindole-3-acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-cyclohexyl-N-thiazol-2-yl-1-(4-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetamide | HCID 58618036 | — |
| 용매 | Methanol | HCID 887 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 용매 | Sodium Hydroxide | HCID 14798 | — |
| 생성물 | N-cyclohexyl-N-thiazol-2-yl-5-methoxy-2-methylindole-3-acetamide | HCID 69312574 | — |
반응 단계
A solution of 2.42 g (0.0045 mol) of N-Cyclohexyl-N-thiazol-2-yl-1-(4-chlorobenzoyl)-5-methoxy-2-methylindole-3-acetamide in 2.4 mL of dichloromethane, 48 mL of methanol and 24 mL of 1N aqueous NaOH solution was stirred at rt for 90 min. During this time, the title compound formed as a precipitate. It was filtered, washed with water and dried.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07414067B2 |
| 출처 데이터셋 | uspto-grants-2008_08 |
| ORD ID | ord-6ad97f6b63e94092b3ac9cc48e6d7a92 |
| 출처 메모 | uspto-grants-2008_08 |