Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
7-Benzyloxy-1-methylindole → 1-methyl-1H-indol-7-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 7-Benzyloxy-1-methylindole | HCID 22136813 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 1-methyl-1H-indol-7-ol | HCID 22136802 | 87% |
반응 단계
To a solution of 7-benzyloxy-1methyl-1H-indole in 20 mL of ethanol was added 10% palladium on charcoal (0.2 g). This solution was stirred under balloon pressure hydrogen atmosphere for 4 h, then filtered through celite and concentrated in vacuo. This material was purified by flash chromatography, eluting silica gel with hexane:ethyl acetate (100:0 to 50:50) to give the product (0.58 g, 87%); Mass spectrum (TOF): m/z=147.1 (M).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07417064B2 |
| 출처 데이터셋 | uspto-grants-2008_08 |
| ORD ID | ord-9f3a6c4a78474b19bcce4612e59c317d |
| 출처 메모 | uspto-grants-2008_08 |