Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanethiol → 1-(1-Methyl-4-pyrazolylmethyl)2-(nitromethylene)tetrahydropyrimidine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanethiol | HCID 878 | — |
| 반응물 | 1,1-Bis(methylthio)-2-nitroethylene | HCID 83623 | — |
| 반응물 | N-(1-methyl-4-pyrazolylmethyl)trimethylenediamine | HCID 14207161 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 1-(1-Methyl-4-pyrazolylmethyl)2-(nitromethylene)tetrahydropyrimidine | HCID 70249087 | 70.1% |
반응 단계
A mixture of 16.8 g of N-(1-methyl-4-pyrazolylmethyl)-trimethylenediamine, 16.5 g of 1-nitro-2,2-bis(methylthio)ethylene and 200 ml of ethanol was heated under reflux until the generation of methylmercaptan ceased. The mixture was cooled, and the precipitated crystals were collected by filtration. Washing with methanol gave 16.6 g of the desired 1-(1-methyl-4-pyrazolylmethyl)2-(nitromethylene)tetrahydropyrimidine as pale yellow crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05428032 |
| 출처 데이터셋 | uspto-grants-1995_06 |
| ORD ID | ord-2bc2df6bc147415a9b2cca3c9d532670 |
| 출처 메모 | uspto-grants-1995_06 |