O-Phenylhydroxylamine → 1-(4-Fluorobenzyl)-N-phenoxy-1H-imidazo[4,5-c]pyridine-6-carboxamide

HRID 2221495

반응식

[F:1][C:2]1[CH:20]=[CH:19][C:5]([CH2:6][N:7]2[C:15]3[CH:14]=[C:13]([C:16]([OH:18])=O)[N:12]=[CH:11][C:10]=3[N:9]=[CH:8]2)=[CH:4][CH:3]=1.[O:21]([NH2:28])[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][N:7]2[C:15]3[CH:14]=[C:13]([C:16]([NH:28][O:21][C:22]4[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=4)=[O:18])[N:12]=[CH:11][C:10]=3[N:9]=[CH:8]2)=[CH:19][CH:20]=1

참가 물질

반응물 2

HCID 2794249O-Phenylhydroxylamine

HCID 218922171-(4-fluoro-benzyl)-1H-imidazo[4,5-c]pyridine-6-carboxylic acid

생성물 1

HCID 104063311-(4-Fluorobenzyl)-N-phenoxy-1H-imidazo[4,5-c]pyridine-6-carboxamide

실험 절차

The title compound can be prepared from 1-(4-fluoro-benzyl)-1H-imidazo[4,5-c]pyridine-6-carboxylic acid and N-phenoxyamine under the same conditions as those in step (c) of Example 1.

출처 및 근거

ORD 기록: ord-74bea9ea313c49b4a17de4750c0e04c3
출처 데이터셋: uspto-grants-2008_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07368571B2

연결된 노트

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