1-Bromo-4-isopropylbenzene → 5,5'-Bis(4-isopropylphenyl)-2,2'-bithiophene

HRID 2222067노트

반응식

HRID 2222067 반응식
C([Sn](CCCC)(CCCC)[C:6]1[S:10][C:9]([C:11]2[S:12][C:13]([Sn](CCCC)(CCCC)CCCC)=[CH:14][CH:15]=2)=[CH:8][CH:7]=1)CCC.Br[C:38]1[CH:43]=[CH:42][C:41]([CH:44]([CH3:46])[CH3:45])=[CH:40][CH:39]=1>CN(C)C=O.C1C=CC([P]([Pd]([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1>[CH:44]([C:41]1[CH:42]=[CH:43][C:38]([C:13]2[S:12][C:11]([C:9]3[S:10][C:6]([C:38]4[CH:43]=[CH:42][C:41]([CH:44]([CH3:46])[CH3:45])=[CH:40][CH:39]=4)=[CH:7][CH:8]=3)=[CH:15][CH:14]=2)=[CH:39][CH:40]=1)([CH3:46])[CH3:45]

참가 물질

5

반응물 2

HCID 114621-Bromo-4-isopropylbenzeneHCID 10533055Agn-PC-0N63KQ

생성물 1

HCID 687616785,5'-Bis(4-isopropylphenyl)-2,2'-bithiophene수율 61.6%

시약·촉매·용매 2

HCID 178418397HCID 178418397, 화합물촉매HCID 6228Dimethylformamide용매

실험 절차

A solution of 1.8 g of 5,5′-bis(tributylstannyl)-2,2′-bithiophene, 1.3 g of 1-bromo-4-isopropylbenzene, and 80 mg of Pd(PPh3)4 in 35 milliliters (“mL”) of N,N-dimethylformamide was heated at 70° C. for 2 days under nitrogen. After cooling, 0.6 g of yeliow-green solid was obtained after washing with methanol and ether, verified pure by nuclear magnetic resonance spectroscopy (“NMR”), and used directly for film and crystal studies.

후처리

  1. temperatureAfter cooling

출처 및 근거

ORD 기록
ord-d1b301ef349f4d06b737435f840c765a
출처 데이터셋
uspto-grants-2008_05
특허 번호
US07371605B2

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