Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Azabicyclo(2.2.2)octane → 2-Aza-bicyclo[2.2.2]octane-2-carboxylic acid [4-methoxy-7-(tetrahydro-pyran-4-yl)-benzothiazol-2-yl]-amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Azabicyclo(2.2.2)octane | HCID 9236 | — |
| 반응물 | Phenyl chloroformate | HCID 15891 | — |
| 반응물 | 4-Methoxy-7-(tetrahydro-pyran-4-yl)-benzothiazol-2-yl-amine | HCID 22015735 | — |
| 생성물 | 2-Aza-bicyclo[2.2.2]octane-2-carboxylic acid [4-methoxy-7-(tetrahydro-pyran-4-yl)-benzothiazol-2-yl]-amide | HCID 11384069 | — |
반응 단계
Using 4-methoxy-7-(tetrahydro-pyran-4-yl)-benzothiazol-2-ylamine, phenyl chloroformate and 2-aza-bicyclo[2.2.2]octane, the title compound was prepared as off-white crystals (53% yield). MS: m/e=402(M+H+), mp 237-239° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07371748B2 |
| 출처 데이터셋 | uspto-grants-2008_05 |
| ORD ID | ord-0de5a3b0151c44e7b1a777f62343ef92 |
| 출처 메모 | uspto-grants-2008_05 |