2-(Oxolan-2-yl)acetic acid → HCID 86595154, 화합물

HRID 2222177노트

반응식

HRID 2222177 반응식
[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([NH2:12])[S:11][C:7]=2[C:6]([CH:13]2[CH2:18][CH2:17][O:16][CH2:15][CH2:14]2)=[CH:5][CH:4]=1.[O:19]1[CH2:23][CH2:22][CH2:21][CH:20]1[CH2:24][C:25](O)=[O:26].COC1C2N=C(NC(=O)CC3CCOCC3)SC=2C(C2CCOCC2)=CC=1>>[CH3:1][O:2][C:3]1[C:8]2[N:9]=[C:10]([NH:12][C:25](=[O:26])[CH2:24][CH:20]3[CH2:21][CH2:22][CH2:23][O:19]3)[S:11][C:7]=2[C:6]([CH:13]2[CH2:18][CH2:17][O:16][CH2:15][CH2:14]2)=[CH:5][CH:4]=1

참가 물질

4

반응물 3

HCID 2287262-(Oxolan-2-yl)acetic acidHCID 11257802HCID 11257802, 화합물HCID 220157354-Methoxy-7-(tetrahydro-pyran-4-yl)-benzothiazol-2-yl-amine

생성물 1

HCID 86595154HCID 86595154, 화합물

실험 절차

Using 4-methoxy-7-(tetrahydro-pyran-4-yl)-benzothiazol-2-ylamine and (tetrahydro-furan-2-yl)-acetic acid, the title compound was prepared in the same manner as described for N-[4-methoxy-7-(tetrahydro-pyran-4-yl)-benzothiazol-2-yl]-2-(tetrahydro-pyran-4-yl)-acetamide and obtained as white solid (50% yield). Mp 170-174° C., MS: m/e=377(M+H+).

출처 및 근거

ORD 기록
ord-e09fdb9649a742eb815a3702b02fb18d
출처 데이터셋
uspto-grants-2008_05
특허 번호
US07371748B2

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