Dimethylformamide → 3-Fluoro-4-(morpholin-3-on-4-yl)benzoic acid-chloride
반응식
[C:1]([CH2:4][O:5][CH2:6][CH2:7][NH:8][C:9]1[CH:17]=[CH:16][C:12]([C:13](O)=[O:14])=[CH:11][C:10]=1[F:18])(O)=[O:2].S(Cl)([Cl:21])=O.CN(C=O)C>ClCCl>[F:18][C:10]1[CH:11]=[C:12]([CH:16]=[CH:17][C:9]=1[N:8]1[CH2:7][CH2:6][O:5][CH2:4][C:1]1=[O:2])[C:13]([Cl:21])=[O:14]참가 물질
5
실험 절차
Prepared analogously to Example 41c from 4-(2-carboxymethoxy-ethylamino)-3-fluoro-benzoic acid and thionylchoride in dichloromethane with DMF.
출처 및 근거
- ORD 기록
- ord-22891a75173042fe88f77edd9993467c
- 출처 데이터셋
- uspto-grants-2008_05
- 특허 번호
- US07371743B2
반응 노트
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