Diethyl allylmalonate → N-(3,5-Difluoro-benzyl)-2-allyl-malonamic acid

HRID 2223256노트

반응식

HRID 2223256 반응식
[F:1][C:2]1[CH:3]=[C:4]([CH:14]=[C:15]([F:17])[CH:16]=1)[CH2:5][NH:6][C:7](=[O:13])[CH:8]([CH3:12])[C:9]([OH:11])=[O:10].[CH2:18](C(C(OCC)=O)C(OCC)=O)[CH:19]=C>>[F:1][C:2]1[CH:3]=[C:4]([CH:14]=[C:15]([F:17])[CH:16]=1)[CH2:5][NH:6][C:7](=[O:13])[CH:8]([CH2:12][CH:18]=[CH2:19])[C:9]([OH:11])=[O:10]

참가 물질

3

반응물 2

HCID 74900Diethyl allylmalonateHCID 21091473N-(3,5-difluoro-benzyl)-2-methyl-malonamic acid

생성물 1

HCID 69280080N-(3,5-Difluoro-benzyl)-2-allyl-malonamic acid

실험 절차

N-(3,5-Difluoro-benzyl)-2-allyl-malonamic acid was prepared in analogy to N-(3,5-difluoro-benzyl)-2-methyl-malonamic acid (example 1) from diethyl allyl-malonate.

출처 및 근거

ORD 기록
ord-d07ec1d66af3435da725d2c7c06400c6
출처 데이터셋
uspto-grants-2008_05
특허 번호
US07375099B2

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