2,6-Dimethylbenzoic acid → 2,6-Dimethylbenzoyl chloride

HRID 222392

반응식

HRID 222392 반응식
[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([CH3:11])[C:3]=1[C:4](O)=[O:5].S(Cl)([Cl:14])=O>C1(C)C=CC=CC=1>[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([CH3:11])[C:3]=1[C:4]([Cl:14])=[O:5]

참가 물질

4

반응물 2

HCID 124392,6-Dimethylbenzoic acidHCID 24386Thionyl Chloride

생성물 1

HCID 890962,6-Dimethylbenzoyl chloride

시약·촉매·용매 1

HCID 1140Toluene용매2회

실험 절차

To a mixture of 2,6-dimethylbenzoic acid (3 g; 0.02 mol) in toluene (50 ml) was added thionyl chloride (3.6 ml; 0.05 mol). The mixture thus obtained was refluxed for 2 hours. The solvent and the excess thionyl chloride were then evaporated off under reduced pressure. The residue thus obtained was taken up in toluene (50 ml) three times and evaporated under reduced pressure. The product thus obtained (3.6 g) was used without further purification.

후처리

  1. customThe mixture thus obtained
  2. temperaturewas refluxed for 2 hours
  3. customThe solvent and the excess thionyl chloride were then evaporated off under reduced pressure
  4. customThe residue thus obtained
  5. customevaporated under reduced pressure
  6. customThe product thus obtained (3.6 g)
  7. customwas used without further purification

출처 및 근거

ORD 기록
ord-396b2865b8034330a6403c08a42ebb9e
출처 데이터셋
uspto-grants-2012_06
특허 번호
US08207214B2

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