3-Iodopicolinic acid → (3-Iodopyridin-2-yl)methanol

HRID 2224345노트

반응식

HRID 2224345 반응식
[I:1][C:2]1[C:3]([C:8](O)=[O:9])=[N:4][CH:5]=[CH:6][CH:7]=1.ClC1C(CO)=CC(F)=C(Cl)N=1>>[I:1][C:2]1[C:3]([CH2:8][OH:9])=[N:4][CH:5]=[CH:6][CH:7]=1

참가 물질

3

반응물 2

HCID 112536923-Iodopicolinic acidHCID 23114857(2,6-Dichloro-5-fluoropyridin-3-yl)methanol

생성물 1

HCID 59717577(3-Iodopyridin-2-yl)methanol수율 10.6%

실험 절차

Compound 51A (10 mg, 10%) was prepared from 3-iodo-pyridine-2-carboxylic acid (100 mg, 0.4 mmol) ) using a procedure similar to the synthesis of 1A. HPLC Rt=0.3 min

출처 및 근거

ORD 기록
ord-d37374855e164e74b6f18014674ccef6
출처 데이터셋
uspto-grants-2008_05
특허 번호
US07378426B2

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