5-Bromo-2-chloro-3-methylpyridine → 5-Bromo-3-(bromomethyl)-2-chloropyridine

반응식

[Br:1][C:2]1[CH:3]=[C:4]([CH3:9])[C:5]([Cl:8])=[N:6][CH:7]=1.[Br:10]C1C(CBr)=NC(Cl)=CC=1>>[Br:1][C:2]1[CH:3]=[C:4]([CH2:9][Br:10])[C:5]([Cl:8])=[N:6][CH:7]=1

참가 물질

반응물 2

HCID 2854345-Bromo-2-chloro-3-methylpyridine

HCID 232499153-Bromo-2-(bromomethyl)-6-chloropyridine

생성물 1

HCID 597175505-Bromo-3-(bromomethyl)-2-chloropyridine수율 33%

실험 절차

Compound 76B (0.46 g, 33%) was prepared from 76A (1.0 g, 4.9 mmol) using a procedure similar to the synthesis of 55B.

출처 및 근거

ORD 기록: ord-41cec1ecd8004f7fbfe3e03c8b6726a1
출처 데이터셋: uspto-grants-2008_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07378426B2

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