Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethyl chlorophosphate → HCID 178475398, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethyl chlorophosphate | HCID 13139 | — |
| 반응물 | 3,4-Diacetoxycinnamic acid | HCID 99103 | — |
| 반응물 | Caffeic Acid | HCID 689043 | — |
| 반응물 | HCID 178483797 | HCID 178483797 | — |
| 촉매 | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 용매 | Triethylamine | HCID 8471 | — |
| 생성물 | HCID 178475398 | HCID 178475398 | — |
반응 단계
Using 3.4 g of 3,4-diacetoxycinnamic acid derived from caffeic acid by the acetylation thereof, 2.8 ml of diethyl chlorophosphate, 2.7 ml of triethylamine, 100 ml of methylene chloride, 3.0 ml of N-(2-dimethylaminoethyl)-trans-4-methylcyclohexylamine (Example 78), and 0.5 g of 4-dimethylaminopyridine, a reaction similar to that conducted in Example 81 was carried out. As a result, 0.68 g of N-(2-dimethylaminoethyl)-N-(trans-4-methylcyclohexyl)-3,4-diacetoxycinnamamide (a compound of the present invention) was obtained as pale yellow crystal, which had the following physiochemical properties:
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05344845 |
| 출처 데이터셋 | uspto-grants-1994_09 |
| ORD ID | ord-2991a9b4149447f3a582a4b3de1d9c97 |
| 출처 메모 | uspto-grants-1994_09 |