Potassium Carbonate → HCID 178490515, 화합물

HRID 2225559노트

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HRID 2225559 반응식
[CH3:1][C@H:2]1[CH2:7][CH2:6][C@H:5]([NH:8][C:9](=[O:24])[CH:10]=[CH:11][C:12]2[CH:17]=[CH:16][C:15]([O:18]C(=O)C)=[C:14]([O:22][CH3:23])[CH:13]=2)[CH2:4][CH2:3]1.C(=O)([O-])[O-].[K+].[K+]>CO>[CH3:1][C@H:2]1[CH2:3][CH2:4][C@H:5]([NH:8][C:9](=[O:24])[CH:10]=[CH:11][C:12]2[CH:17]=[CH:16][C:15]([OH:18])=[C:14]([O:22][CH3:23])[CH:13]=2)[CH2:6][CH2:7]1

참가 물질

4

반응물 2

HCID 11430Potassium CarbonateHCID 178490553HCID 178490553, 화합물

생성물 1

HCID 178490515HCID 178490515, 화합물수율 85.1%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

Using 3.7 g of N-(trans-4-methylcyclohexyl)-4-acetoxy-3-methoxycinnamamide (Example 130), 100 ml of methanol, and 5 g of potassium carbonate, a reaction similar to that conducted in Example 105 was carried out. As a result, 2.75 g of N-(trans-4-methylcyclohexyl)-4-hydroxy-3-methoxycinnamamide (a compound of the present invention) was obtained as white crystal, which had the following physiochemical properties:

후처리

  1. customa reaction similar to

출처 및 근거

ORD 기록
ord-1f4b22497cae40868e9dc7a3cd02fbae
출처 데이터셋
uspto-grants-1994_09
특허 번호
US05344845

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