Water → 4-[2-(4-(4-Methyl-3-pentenyl)-3-cyclohexenyl)ethyl]phenol

HRID 2227103노트

반응식

HRID 2227103 반응식
[CH3:1][C:2]([CH3:22])=[CH:3][CH2:4][CH2:5][C:6]1[CH2:11][CH2:10][CH:9]([CH2:12][CH2:13][C:14]2[CH:19]=[CH:18][C:17]([O:20]C)=[CH:16][CH:15]=2)[CH2:8][CH:7]=1.B(Br)(Br)Br.O>ClCCl>[CH3:1][C:2]([CH3:22])=[CH:3][CH2:4][CH2:5][C:6]1[CH2:11][CH2:10][CH:9]([CH2:12][CH2:13][C:14]2[CH:15]=[CH:16][C:17]([OH:20])=[CH:18][CH:19]=2)[CH2:8][CH:7]=1

참가 물질

5

반응물 3

HCID 962WaterHCID 25134Boron tribromideHCID 184718172-(4-(4-Methyl-3-pentenyl)-3-cyclohexenyl)ethyl-4-methoxybenzene

생성물 1

HCID 184718234-[2-(4-(4-Methyl-3-pentenyl)-3-cyclohexenyl)ethyl]phenol

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

To a solution of anisole 2F (R=4-Methyl-3-pentenyl) (6 g) in dichloromethane (100 mL) and cooled in an ice bath is added a 1M solution of boron tribromide (3.4 mL). The solution is stirred for one hour, then poured into water. The reaction mixture is extracted with dichloromethane and dried over magnesium sulfate. The solution is concentrated in vacuo. The product is recrystallized from hexane.

후처리

  1. extractionThe reaction mixture is extracted with dichloromethane
  2. dry with materialdried over magnesium sulfate
  3. concentrationThe solution is concentrated in vacuo
  4. customThe product is recrystallized from hexane

출처 및 근거

ORD 기록
ord-cd9462bf4bf542ca9fff7f6eea480cb0
출처 데이터셋
uspto-grants-2002_07
특허 번호
US06413448B1

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