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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 222714생성일: 2026년 10월 26일

1-(6-Chloropyridin-3-yl)ethan-1-one → 1-{6-[(3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-3-pyridinyl}ethanone

https://huagongshe.com/reaction/222714

반응식

참여 물질

역할이름HCID투입량
반응물1-(6-Chloropyridin-3-yl)ethan-1-oneHCID 2779698—
반응물3-Cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[D]azepin-7-OLHCID 10082081—
반응물6-(3-Cyclobutyl-2,3,4,5-tetrahydro-1h-benzo[c]azepin-7-yloxy)-nicotinonitrileHCID 68601023—
생성물1-{6-[(3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-3-pyridinyl}ethanoneHCID 10065600—

반응 단계

Example 214 (E214) was prepared from 3-cyclobutyl-2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ol (E3) and 1-(6-chloropyridin-3-yl)ethanone using the method described for Example 100 (E100); MS (ES+) m/e 337 [M+H]+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08207331B2
출처 데이터셋uspto-grants-2012_06
ORD IDord-4eb0db71cb23487d93162e5c10fb9e93
출처 메모uspto-grants-2012_06