2-Oxazolidinone → 3-{5-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-2-pyrazinyl}-1,3-oxazolidin-2-one
반응식
Br[C:2]1[N:3]=[CH:4][C:5]([O:8][C:9]2[CH:23]=[CH:22][C:12]3[CH2:13][CH2:14][N:15]([CH:18]4[CH2:21][CH2:20][CH2:19]4)[CH2:16][CH2:17][C:11]=3[CH:10]=2)=[N:6][CH:7]=1.[O:24]1[CH2:28][CH2:27][NH:26][C:25]1=[O:29]>>[CH:18]1([N:15]2[CH2:14][CH2:13][C:12]3[CH:22]=[CH:23][C:9]([O:8][C:5]4[N:6]=[CH:7][C:2]([N:26]5[CH2:27][CH2:28][O:24][C:25]5=[O:29])=[N:3][CH:4]=4)=[CH:10][C:11]=3[CH2:17][CH2:16]2)[CH2:21][CH2:20][CH2:19]1참가 물질
3
실험 절차
The title compound was prepared from 7-[(5-bromo-2-pyrazinyl)oxy]-3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepine (E259) and oxazolidinone using the method of Example 258 (E258); MS (ES+) m/e 381 [M+H]+.
출처 및 근거
- ORD 기록
- ord-b4d12fd61c474081a85e29a1a25e87cc
- 출처 데이터셋
- uspto-grants-2012_06
- 특허 번호
- US08207331B2
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