Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Formaldehyde → 5-Methoxy-2-methylindan-1-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Formaldehyde | HCID 712 | — |
| 반응물 | Hexane | HCID 8058 | — |
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | 5-Methoxyindan-1-one | HCID 78787 | — |
| 촉매 | Pentacarbonyliron(0) | HCID 518773 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | 5-Methoxy-2-methylindan-1-one | HCID 12290490 | 44% |
반응 단계
5-Methoxy indanone was treated with aqueous formaldehyde in the presence of iron pentacarbonyl and KOH in ethanol according to G. Cainelli et. al., Tetrahedron Letters 27, 2491 (1973). After chromatography (hexane:ethylacetate=7:3) over SiO2, a 44% yield of white crystals was obtained (m.p. 73-76° C.).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06416746B1 |
| 출처 데이터셋 | uspto-grants-2002_07 |
| ORD ID | ord-25fd0c8a62c34b399dc7840abb978e0e |
| 출처 메모 | uspto-grants-2002_07 |