Ethyl chloroformate → 2-Cyclohexyl-2,3-dihydro-6-[4-(ethoxycarbonyl)-piperazin-1-yl]-1H-isoindol-1-one
반응식
[CH:1]1([N:7]2[CH2:15][C:14]3[C:9](=[CH:10][C:11]([N:16]4[CH2:21][CH2:20][NH:19][CH2:18][CH2:17]4)=[CH:12][CH:13]=3)[C:8]2=[O:22])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH2:23]([O:25][C:26](Cl)=[O:27])[CH3:24]>>[CH:1]1([N:7]2[CH2:15][C:14]3[C:9](=[CH:10][C:11]([N:16]4[CH2:17][CH2:18][N:19]([C:26]([O:25][CH2:23][CH3:24])=[O:27])[CH2:20][CH2:21]4)=[CH:12][CH:13]=3)[C:8]2=[O:22])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1참가 물질
3
실험 절차
In the same manner as in Example 28, the title compound was prepared from the compound obtained in step (e) of Example 1 and ethoxycarbonyl chloride.
출처 및 근거
- ORD 기록
- ord-4f036aaa58914557a78c93461302cf38
- 출처 데이터셋
- uspto-grants-2002_07
- 특허 번호
- US06417362B1
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