Methyl 2-hydroxy-2-(4-methoxyphenyl)acetate → 2-(3,5-Dimethoxyphenyl)-2-tetrahydrofuroic acid

HRID 2229491노트

반응식

HRID 2229491 반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:12]=[C:13]([O:15][CH3:16])[CH:14]=1)[CH:6]([OH:11])[C:7]([O:9]C)=[O:8].CO[C:19]1[CH:30]=CC(C(O)C(OC)=O)=C[CH:20]=1>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:6]2([C:7]([OH:9])=[O:8])[CH2:30][CH2:19][CH2:20][O:11]2)[CH:12]=[C:13]([O:15][CH3:16])[CH:14]=1

참가 물질

3

반응물 2

HCID 523496Methyl 2-hydroxy-2-(4-methoxyphenyl)acetateHCID 62214124Methyl 2-(3,5-dimethoxyphenyl)-2-hydroxyacetate

생성물 1

HCID 184678662-(3,5-Dimethoxyphenyl)-2-tetrahydrofuroic acid

실험 절차

2-(3,5-Dimethoxyphenyl)-2-tetrahydrofuroic acid was prepared according to the procedures described in Reference Example 27 substituting 3,5-dimethoxymandelic acid, methyl ester for 4-methoxymandelic acid, methyl ester in Step A.

출처 및 근거

ORD 기록
ord-342b9add2ed5478aac2b0fbe2853b273
출처 데이터셋
uspto-grants-2002_07
특허 번호
US06420418B1

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