Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Phenylpiperazine → 7-methoxy-6-[3-(4-phenyl-1-piperazinyl)propoxy]-2H-1-benzopyran-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Phenylpiperazine | HCID 7096 | — |
| 반응물 | Fumarate | HCID 5460307 | — |
| 반응물 | 6-[3-(methanesulfonyloxy)propoxy]-7-methoxy-2H-1-benzopyran-2-one | HCID 19927727 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 7-methoxy-6-[3-(4-phenyl-1-piperazinyl)propoxy]-2H-1-benzopyran-2-one | HCID 19927644 | 55% |
반응 단계
Method A (23 h at 60° C.); starting materials: 6-[3-(methanesulfonyloxy)propoxy]-7-methoxy-2H-1-benzopyran-2-one (see example 67) and 1-phenylpiperazine; yield 55%; fusion point 124° to 125° C. (from ethanol). Fumarate: method E; yield 88%; fusion point 172° to 173° C. (from ethanol).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05428038 |
| 출처 데이터셋 | uspto-grants-1995_06 |
| ORD ID | ord-4e9e7528c2ef4b708c884f4ab638ad29 |
| 출처 메모 | uspto-grants-1995_06 |