Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → 7-ethoxy-6-[3-(4-phenyl-1-piperazinyl)propoxy]-2H-1-benzopyran-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | 1-Phenylpiperazine | HCID 7096 | — |
| 반응물 | Fumarate | HCID 5460307 | — |
| 반응물 | 6-(3-chloropropoxy)-7-ethoxy-2H-1-benzopyran-2-one | HCID 19927734 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 7-ethoxy-6-[3-(4-phenyl-1-piperazinyl)propoxy]-2H-1-benzopyran-2-one | HCID 19927661 | 57% |
반응 단계
Method A (26 h at 60° C.); starting materials: 6-(3-chloropropoxy)-7-ethoxy-2H-1-benzopyran-2-one (see example 70) and 1-phenylpiperazine; yield 57%; fusion point 151° to 153° (from methanol and ethanol). Fumarate: method E; yield 78%; fusion point 170° to 173° C. (from ethanol).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05428038 |
| 출처 데이터셋 | uspto-grants-1995_06 |
| ORD ID | ord-d60a35bd97fd4ef6ac58e78b0a9da410 |
| 출처 메모 | uspto-grants-1995_06 |