Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(1(S)-Benzyloxycarbonyl-3-methylbutyl)-3-azido-4-phenylazetidin-2-one → L-Phenylalanyl-L-leucine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(1(S)-Benzyloxycarbonyl-3-methylbutyl)-3-azido-4-phenylazetidin-2-one | HCID 22821671 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | L-Phenylalanyl-L-leucine | HCID 76808 | — |
반응 단계
1-(1(S)-Benzyloxycarbonyl-3-methylbutyl)-3-azido-4-phenylazetidin-2-one (200 mg., 0.51 mmol) was hydrogenated in 10 ml. of ethanol at 50° C. for 19 hours under ambient pressure using a 10% Pd-C (270 mg.) as a catalyst to give D/L-phenylalanyl-L-leucine quantitatively.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04352752 |
| 출처 데이터셋 | uspto-grants-1982_10 |
| ORD ID | ord-420b9636b1154624a8cf612f4ce600e2 |
| 출처 메모 | uspto-grants-1982_10 |