Sulfuric Acid → Benzene, 1-methyl-4-[1-(chloromethyl)-1-methylethyl]

HRID 223114노트

반응식

HRID 223114 반응식
[CH2:1]([Cl:5])[C:2](=[CH2:4])[CH3:3].S(=O)(=O)(O)O.[C:11]1([CH3:17])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[CH3:4][C:2]([C:14]1[CH:15]=[CH:16][C:11]([CH3:17])=[CH:12][CH:13]=1)([CH3:3])[CH2:1][Cl:5]

참가 물질

4

반응물 3

HCID 1118Sulfuric AcidHCID 1140TolueneHCID 112413-Chloro-2-methyl-1-propene

생성물 1

HCID 524329Benzene, 1-methyl-4-[1-(chloromethyl)-1-methylethyl]수율 85%

실험 절차

24 g Methallyl chloride is added to a mixture of 92 g toluene and 49 g concentrated sulphuric acid, keeping the temperature at 40° C. No exothermal reaction occurs. Subsequently the reaction mixture is stirred during half an hour, after which the layers are separated. The organic layer is washed neutral with soda solution, dried on MgSO4 and evaporated. The residue is distilled under diminished pressure to obtain 2-methyl-2-(p-tolyl)-propyl chloride (p-methyl-neophyl chloride) in a yield of 85%.

후처리

  1. customat 40° C
  2. customNo exothermal reaction
  3. customafter which the layers are separated
  4. washThe organic layer is washed neutral with soda solution
  5. customdried on MgSO4
  6. customevaporated
  7. distillationThe residue is distilled under diminished pressure

출처 및 근거

ORD 기록
ord-ffca0aac55ea4cc9b8da7f6f473e096d
출처 데이터셋
uspto-grants-1982_10
특허 번호
US04352748

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