Ethyl 2-chloroacetoacetate → HCID 178432777, 화합물

HRID 223132

반응식

HRID 223132 반응식
[Cl:1][C:2]([Cl:7])([Cl:6])[C:3]([NH2:5])=[NH:4].[Cl:8][CH:9]([C:15]([CH3:17])=O)[C:10](OCC)=[O:11]>>[Cl:8][C:9]1[C:10]([OH:11])=[N:4][C:3]([C:2]([Cl:7])([Cl:6])[Cl:1])=[N:5][C:15]=1[CH3:17]

참가 물질

3

반응물 2

HCID 11858Ethyl 2-chloroacetoacetateHCID 356082,2,2-Trichloroethanimidamide

생성물 1

HCID 178432777HCID 178432777, 화합물

실험 절차

The carboxylic ester compounds of the present invention may be prepared by reacting trichloroacetamidine with a selected acetoacetate to form the corresponding 4-hydroxy-2-trichloromethylpyrimidine, which is then reacted with a selected carboxylic acid chloride. These general reactions are illustrated below in equations (A) and (B). In equation (A), trichloroacetamidine is reacted with ethyl 2-chloroacetoacetate to form 5-chloro-4-hydroxy-6-methyl-2-trichloromethyl-pyrimidine. In equation (B), the 5-chloro-4-hydroxy-6-methyl-2-trichloromethylpyrimidine is reacted with trichloroacetyl chloride to form 5-chloro-6-methyl-4-trichloroacetoxy-2-trichloromethylpyrimidine. ##STR3##

출처 및 근거

ORD 기록
ord-2aac76d60a114123a162dccf3cc33b16
출처 데이터셋
uspto-grants-1982_10
특허 번호
US04352806

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