Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → HCID 13051398, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | trans-Crotonyl chloride | HCID 643131 | — |
| 반응물 | HCID 178429333 | HCID 178429333 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | HCID 13051398 | HCID 13051398 | 45% |
반응 단계
To a solution of 3.0 g (0.02 mole) 4-hydroxy-6-methyl-2-trichloromethylpyrimidine and 1.3 g (0.02 mole) triethylamine in 75 ml diethyl ether was added 1.4 g (0.02 mole) crotonyl chloride. The reaction mixture was refluxed for 15 hours and filtered, and the filtrate was concentrated in-vacuo to give a viscous oil as residue. Trituration with petroleum ether caused the oil to solidify. Recrystallization from isopropyl alcohol gave 1.8 g (45% yield) of pure product; m.p. 55° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04352806 |
| 출처 데이터셋 | uspto-grants-1982_10 |
| ORD ID | ord-862eea4fe61a46a7a4bd37ce9962335e |
| 출처 메모 | uspto-grants-1982_10 |