Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sulfuric Acid → 7-Chloro-4-methyl-8-nitroisoquinoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | Potassium Nitrate | HCID 24434 | — |
| 반응물 | 7-Chloro-4-methylisoquinoline | HCID 20523223 | — |
| 생성물 | 7-Chloro-4-methyl-8-nitroisoquinoline | HCID 20523218 | — |
반응 단계
A mixture of 17.7 g. (0.1 mole) of 7-chloro-4-methylisoquinoline and 100 ml. of concentrated sulfuric acid is treated with 10 g. (0.1 mole) of potassium nitrate dissolved in 150 ml. of concentrated sulfuric acid. The mixture is stirred for one hour, quenched on ice, made alkaline with ammonium hydroxide and filtered to yield 7-chloro-4-methyl-8-nitroisoquinoline.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04352809 |
| 출처 데이터셋 | uspto-grants-1982_10 |
| ORD ID | ord-153a648d1b2f46eea8d8e5555ee8287b |
| 출처 메모 | uspto-grants-1982_10 |