Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Indole → 7-Ethyl-1,1a,2,3,8,8b-hexahydrocyclopropa[a]-carbazole-8b-acetic Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Indole | HCID 798 | — |
| 반응물 | (2-Ethylphenyl)hydrazine | HCID 2733210 | — |
| 반응물 | 2-Oxobicyclo[4.1.0]heptane-1-acetic Acid Ethyl Ester | HCID 14770207 | — |
| 생성물 | 7-Ethyl-1,1a,2,3,8,8b-hexahydrocyclopropa[a]-carbazole-8b-acetic Acid | HCID 14302244 | — |
반응 단계
The title compound was prepared from 2-oxobicyclo[4.1.0]heptane-1-acetic acid ethyl ester by a Fisher indole reaction with 2-ethylphenylhydrazine followed by ester hydrolysis as described in Example 1, Step 6, m.p. 154°-156° C. (foams).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04783479 |
| 출처 데이터셋 | uspto-grants-1988_11 |
| ORD ID | ord-f46c9e10c14d43f1ae07df682059d662 |
| 출처 메모 | uspto-grants-1988_11 |