Ammonia → 2,3,5-Trimethylpyridine

HRID 2231948노트

반응식

HRID 2231948 반응식
Cl[C:2]1[C:7]([CH3:8])=[C:6](Cl)[N:5]=[C:4]([CH3:10])[C:3]=1[CH3:11].N.[H][H]>C(O)C.[Pd]>[CH3:10][C:4]1[C:3]([CH3:11])=[CH:2][C:7]([CH3:8])=[CH:6][N:5]=1

참가 물질

6

반응물 3

HCID 222AmmoniaHCID 27791392,4-Dichloro-3,5,6-trimethylpyridineHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 127592,3,5-Trimethylpyridine

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

20 g 4,6-dichloro-2,3,5 trimethylpyridine was dissolved in 150 ml ethanol and 1 g 10% Pd/C and 10 ml conc. aqueous ammonia. The hydrogenation was performed at 3 bar for 3 hrs when the calculated amount of hydrogen had been adsorbed. Evaporation of solvent gave the 2,3,5-trimethylpyridine.

후처리

  1. customEvaporation of solvent

출처 및 근거

ORD 기록
ord-b1bbbf7fd11b48a6b34e18dd717dbbfa
출처 데이터셋
uspto-grants-1988_11
특허 번호
US04785113

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