m-Chloroperbenzoic acid → HCID 21283336, 화합물

HRID 2232233노트

반응식

HRID 2232233 반응식
ClC1C=CC=C(C(OO)=[O:9])C=1.[CH3:12][O:13][C:14]1[CH:19]=[CH:18][C:17]([C:20]2[C:29]3[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=3)[C:23]3=[N:30][N:31]=[C:32]([S:33][CH3:34])[N:22]3[N:21]=2)=[CH:16][CH:15]=1>C(Cl)Cl>[CH3:12][O:13][C:14]1[CH:19]=[CH:18][C:17]([C:20]2[C:29]3[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=3)[C:23]3=[N:30][N:31]=[C:32]([S:33]([CH3:34])=[O:9])[N:22]3[N:21]=2)=[CH:16][CH:15]=1

참가 물질

4

반응물 2

HCID 70297m-Chloroperbenzoic acidHCID 21283334HCID 21283334, 화합물

생성물 1

HCID 21283336HCID 21283336, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

3-Chloroperbenzoic acid (2.2 g) is added to a solution of 6-(4-methoxyphenyl)-3-(methylthio)-1,2,4-triazolo[3,4-a]phthalazine (4 g) in methylene chloride (120 ml) and the obtained mixture is stirred at room temperature for 5 hours. The solution is washed with sodium metabisulfite first and then with sodium bicarbonate. The organic solution is then dried over MgSO4 and concentrated to dryness by evaporating off the solvent. The residue thus obtained is crystallized from ethanol yielding 4 g of the compound of the title. M.p. 201°-03° C.

후처리

  1. washThe solution is washed with sodium metabisulfite first
  2. dry with materialThe organic solution is then dried over MgSO4
  3. concentrationconcentrated to dryness
  4. customby evaporating off the solvent
  5. customThe residue thus obtained
  6. customis crystallized from ethanol yielding 4 g of the compound of the title

출처 및 근거

ORD 기록
ord-350290d39b944b0786a02776330d47bd
출처 데이터셋
uspto-grants-1988_11
특허 번호
US04788186

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