Chlorosuccinimide → HCID 21283210, 화합물

HRID 2232427노트

반응식

HRID 2232427 반응식
[NH2:1][C:2]1[S:3][CH:4]=[C:5](/[C:7](=[N:11]/[O:12][CH2:13][C:14]([O:16][C:17]([CH3:20])([CH3:19])[CH3:18])=[O:15])/[C:8]([OH:10])=[O:9])[N:6]=1.[Cl:21]N1C(=O)CCC1=O>CCCCCC>[NH2:1][C:2]1[S:3][C:4]([Cl:21])=[C:5](/[C:7](=[N:11]/[O:12][CH2:13][C:14]([O:16][C:17]([CH3:20])([CH3:19])[CH3:18])=[O:15])/[C:8]([OH:10])=[O:9])[N:6]=1

참가 물질

4

반응물 2

HCID 31398ChlorosuccinimideHCID 10870340HCID 10870340, 화합물

생성물 1

HCID 21283210HCID 21283210, 화합물수율 97.2%

시약·촉매·용매 1

HCID 8058Hexane용매

실험 절차

Six grams of 2-(2-aminothiazol-4-yl)-2(Z)-(tert-butoxycarbonylmethoxyimino)acetic acid and 3.2 g of N-chlorosuccinimide are reacted in the manner of Reference Example 35 and the product obtained is solidified by treating hexane to give 6.5 g of the above-identified compound as a powder.

후처리

  1. customthe product obtained

출처 및 근거

ORD 기록
ord-fa64692bea1f4361b1cdfcbe344f2125
출처 데이터셋
uspto-grants-1988_11
특허 번호
US04788185

반응 노트

불러오는 중…