3-Aminopropionitrile → 2-(1,3-Benzothiazol-2-yl)ethan-1-amine
반응식
[NH2:1][CH2:2][CH2:3][C:4]#[N:5].N[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[SH:13]>CCO>[S:13]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[N:5]=[C:4]1[CH2:3][CH2:2][NH2:1]참가 물질
4
실험 절차
A solution of 50 mg of 3-aminopropionitrile and 596 mg of 2-aminothiophenol in EtOH (15 mL) was heated at reflux for six h. After cooling the solution to room temperature, the reaction was concentrated and the residue was purified by silica gel chromatography to afford the title compound as a red oil. MS (M+H)+=179.1.
후처리
- temperatureat reflux for six h
- concentrationthe reaction was concentrated
- customthe residue was purified by silica gel chromatography
출처 및 근거
- ORD 기록
- ord-1fd12dcc2a8149c4a2a880aee1a32940
- 출처 데이터셋
- uspto-grants-2010_05
- 특허 번호
- US07709473B2
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