참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 4-Aminophenol | HCID 403 | — |
| 반응물 | Acetone Cyanohydrin | HCID 6406 | — |
| 반응물 | Sulfuric acid magnesium salt (1:1) | HCID 24083 | — |
| 생성물 | 2-(4-Hydroxyphenylamino)-2-methylpropanenitrile | HCID 350269 | 96% |
반응 단계
A mixture of 4-aminophenol (1.09 g, 10 mmol), acetone cyanohydrin (10 ml) and MgSO4 (2 g) was heated to 80° C. and stirred for 4 h. After concentration of the medium under vacuum, compound 3a was crystallized from water (20 ml). The solid was filtered and dried to yield 2-(4-hydroxyphenylamino)-2-methylpropanenitrile, 3a (1.69 g, 9.6 mmol, 96%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07709517B2 |
|---|
| 출처 데이터셋 | uspto-grants-2010_05 |
|---|
| ORD ID | ord-0cb27252f9b747538627e043f3f082ed |
|---|
| 출처 메모 | uspto-grants-2010_05 |
|---|
