Methyl 3-cyano-5-methyl-1H-pyrrole-2-carboxylate → 4-Bromo-3-cyano-5-methyl-1H-pyrrole-2-carboxylic acid

HRID 2233832노트

반응식

HRID 2233832 반응식
[Br:1][C:2]1[C:3]([C:12]#[N:13])=[C:4]([C:9]([OH:11])=[O:10])[NH:5][C:6]=1[CH2:7]C.COC(C1NC(C)=CC=1C#N)=O>>[Br:1][C:2]1[C:3]([C:12]#[N:13])=[C:4]([C:9]([OH:11])=[O:10])[NH:5][C:6]=1[CH3:7]

참가 물질

3

반응물 2

HCID 10797098Methyl 3-cyano-5-methyl-1H-pyrrole-2-carboxylate2회HCID 685800054-Bromo-3-cyano-5-ethyl-1H-pyrrole-2-carboxylic acid

생성물 1

HCID 580661454-Bromo-3-cyano-5-methyl-1H-pyrrole-2-carboxylic acid

실험 절차

The title compound was prepared by a procedure analogous to Intermediate 33 starting from 3-cyano-5-methyl-1H-pyrrole-2-carboxylic acid methyl ester (Intermediate 28).

출처 및 근거

ORD 기록
ord-5eaf1417fcfe44f18fbfd538b2a12863
출처 데이터셋
uspto-grants-2010_05
특허 번호
US07709503B2

반응 노트

불러오는 중…