4-Bromo-5-methyl-1H-pyrrole-2-carboxylic acid → HCID 68580239, 화합물

HRID 2233847노트

반응식

HRID 2233847 반응식
Cl[C:2]1[C:6](Cl)=[C:5]([CH3:8])[NH:4][C:3]=1[C:9]([NH:11][CH:12]1[CH2:17][CH2:16][N:15]([C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])[CH2:14][CH2:13]1)=[O:10].[Br:25]C1C=C(C(O)=O)NC=1C>>[Br:25][C:6]1[CH:2]=[C:3]([C:9]([NH:11][CH:12]2[CH2:17][CH2:16][N:15]([C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19])[CH2:14][CH2:13]2)=[O:10])[NH:4][C:5]=1[CH3:8]

참가 물질

3

반응물 2

HCID 685182224-Bromo-5-methyl-1H-pyrrole-2-carboxylic acid2회HCID 68579743tert-Butyl 4-{[(3,4-dichloro-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}piperidine-1-carboxylate

생성물 1

HCID 68580239HCID 68580239, 화합물

실험 절차

Title compound was synthesized by an analogous method to Intermediate 2, starting from 4-bromo-5-methyl-1H-pyrrole-2-carboxylic acid (Intermediate 18).

출처 및 근거

ORD 기록
ord-c72244a2c1f441a08df34790a4fe1c0a
출처 데이터셋
uspto-grants-2010_05
특허 번호
US07709503B2

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