3,4-Dichloro-5-methyl-1H-pyrrole-2-carboxylic acid → 3,4-Dichloro-5-cyano-1H-pyrrole-2-carboxylic acid

반응식

ClC1C(Cl)=C(C)NC=1C(O)=O.[Cl:12][C:13]1[C:17]([Cl:18])=[C:16]([C:19]#[N:20])[NH:15][C:14]=1[C:21]([O:23]C)=[O:22]>>[Cl:12][C:13]1[C:17]([Cl:18])=[C:16]([C:19]#[N:20])[NH:15][C:14]=1[C:21]([OH:23])=[O:22]

참가 물질

반응물 2

HCID 251376823,4-Dichloro-5-methyl-1H-pyrrole-2-carboxylic acid

HCID 68582549methyl 3,4-dichloro-5-cyano-1H-pyrrole-2-carboxy late2회

생성물 1

HCID 251376833,4-Dichloro-5-cyano-1H-pyrrole-2-carboxylic acid

실험 절차

The title compound was prepared by a procedure analogous to Intermediate 3 starting from methyl 3,4-dichloro-5-cyano-1H-pyrrole-2-carboxy late (Intermediate 130).

출처 및 근거

ORD 기록: ord-af064eca6d45496eb81e119a7c8ee209
출처 데이터셋: uspto-grants-2010_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07709503B2

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