O-Methylhydroxylamine hydrochloride → HCID 86608313, 화합물

반응식

[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([N:11]2[CH2:16][CH2:15][CH:14]([NH:17][C:18]([C:20]3[NH:21][C:22]([CH3:27])=[C:23]([Cl:26])[C:24]=3[Cl:25])=[O:19])[CH2:13][CH2:12]2)[N:10]=1)[C:5](O)=[O:6].Cl.[O:29]([NH2:31])[CH3:30]>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:8]=[C:9]([N:11]2[CH2:12][CH2:13][CH:14]([NH:17][C:18]([C:20]3[NH:21][C:22]([CH3:27])=[C:23]([Cl:26])[C:24]=3[Cl:25])=[O:19])[CH2:15][CH2:16]2)[N:10]=1)[C:5]([NH:31][O:29][CH3:30])=[O:6]

참가 물질

반응물 2

HCID 521874O-Methylhydroxylamine hydrochloride

HCID 57397809HCID 57397809, 화합물

생성물 1

HCID 86608313HCID 86608313, 화합물

실험 절차

The title compound was synthesised by an analogous method to Example 45 starting from 2-chloro-6-(4-{[(3,4-dichloro-5-methyl-1H-pyrrol-2-yl)carbonyl]amino}piperidin-1-yl)isonicotinic acid (Example 153) and methoxylamine hydrochloride.

출처 및 근거

ORD 기록: ord-0d9ece13e083470fae47798eb6a35574
출처 데이터셋: uspto-grants-2010_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07709503B2

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