HCID 68579996, 화합물 → HCID 68582437, 화합물

HRID 2234053노트

반응식

HRID 2234053 반응식
Cl.[Cl:2][C:3]1[C:7]([Cl:8])=[C:6]([CH3:9])[NH:5][C:4]=1[C:10]([NH:12][CH:13]1[CH2:18][CH2:17][NH:16][CH2:15][CH2:14]1)=[O:11].Cl[C:20]1[CH:21]=[C:22]([CH:27]=[C:28]([S:30]([CH3:32])=[O:31])[N:29]=1)[C:23]([O:25][CH3:26])=[O:24]>>[Cl:2][C:3]1[C:7]([Cl:8])=[C:6]([CH3:9])[NH:5][C:4]=1[C:10]([NH:12][CH:13]1[CH2:18][CH2:17][N:16]([C:20]2[CH:21]=[C:22]([CH:27]=[C:28]([S:30]([CH3:32])=[O:31])[N:29]=2)[C:23]([O:25][CH3:26])=[O:24])[CH2:15][CH2:14]1)=[O:11]

참가 물질

3

반응물 2

HCID 68579996HCID 68579996, 화합물2회HCID 86038392HCID 86038392, 화합물2회

생성물 1

HCID 68582437HCID 68582437, 화합물

실험 절차

The title compound was prepared in a manner analogous to Example 6 starting from 3,4-dichloro-5-methyl-N-piperidin-4-yl-1H-pyrrole-2-carboxamide hydrochloride (Intermediate 1) and methyl 2-chloro-6-(methylsulfinyl)isonicotinate (Intermediate 84).

출처 및 근거

ORD 기록
ord-5f0ff4b673d743038eaf4fa63f42f9c0
출처 데이터셋
uspto-grants-2010_05
특허 번호
US07709503B2

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