Ethyl 2-bromo-1,3-thiazole-4-carboxylate → HCID 68579908, 화합물

HRID 2234055노트

반응식

HRID 2234055 반응식
Cl.[Cl:2][C:3]1[C:7]([Cl:8])=[C:6]([CH3:9])[NH:5][C:4]=1[C:10]([NH:12][CH:13]1[CH2:18][CH2:17][NH:16][CH2:15][CH2:14]1)=[O:11].Br[C:20]1[S:21][CH:22]=[C:23]([C:25]([O:27][CH2:28][CH3:29])=[O:26])[N:24]=1>>[Cl:2][C:3]1[C:7]([Cl:8])=[C:6]([CH3:9])[NH:5][C:4]=1[C:10]([NH:12][CH:13]1[CH2:18][CH2:17][N:16]([C:20]2[S:21][CH:22]=[C:23]([C:25]([O:27][CH2:28][CH3:29])=[O:26])[N:24]=2)[CH2:15][CH2:14]1)=[O:11]

참가 물질

3

반응물 2

HCID 353965Ethyl 2-bromo-1,3-thiazole-4-carboxylateHCID 68579996HCID 68579996, 화합물2회

생성물 1

HCID 68579908HCID 68579908, 화합물

실험 절차

The title compound was prepared in a manner analogous to Example 320 from 3,4-dichloro-5-methyl-N-piperidin-4-yl-1H-pyrrole-2-carboxamide hydrochloride (intermediate 1) and ethyl 2-bromo-1,3-thiazole-4-carboxylate (commercially available).

출처 및 근거

ORD 기록
ord-dccf2eb943674a8698a0bb2afe6d3525
출처 데이터셋
uspto-grants-2010_05
특허 번호
US07709503B2

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